Seahawks vs. Cardinals Week 10 Preview: Can Seattle Sweep Arizona? (2026)

In the NFC West, every game is a battle, and this week’s clash between the Seattle Seahawks and Arizona Cardinals is no exception. With the Seahawks perched atop the division, their Week 10 matchup against the Cardinals could be a defining moment in their season. But here’s where it gets interesting: while Seattle aims for another sweep, the Cardinals are no pushovers this time around. Let’s dive into why this game is far from a sure thing for the Seahawks.

The Seahawks currently lead the NFC West, thanks in part to their earlier victory over Arizona. However, a loss this week would drop them to a concerning 1-2 in division play, with tough games against the Rams and 49ers still on the horizon. And this is the part most people miss: Seattle’s remaining schedule includes formidable opponents like the Minnesota Vikings and Indianapolis Colts, making this game against the Cardinals a must-win to maintain their playoff aspirations.

Both teams have undergone significant transformations since their Week 4 meeting. For Arizona, Kyler Murray is now on IR and likely headed elsewhere next season, with Jacoby Brissett stepping in as quarterback. Brissett has surprisingly outperformed Murray, bringing a more efficient offensive rhythm. Defensively, rookie Walter Nolen has emerged as a game-changer, bolstering the Cardinals’ defensive line. The return of Garrett Williams has also strengthened their secondary, while additions like Will Hernandez and Zay Jones have upgraded their offensive capabilities. Meanwhile, the Cardinals’ backfield now features a tandem of Bam Knight and Emari Demercado, adding versatility to their ground attack.

Seattle, on the other hand, faces key absences. Julian Love and Ernest Jones are out on defense, and Cooper Kupp and Tory Horton may be limited or absent altogether. However, the Seahawks gain reinforcements with the debut of Rashid Shaheed and the return of DeMarcus Lawrence and Nick Emmanwori, who has been a defensive standout. But here’s where it gets controversial: Can Seattle’s retooled defense handle Arizona’s improved offense, especially with Brissett’s ability to extend plays and distribute the ball effectively?**

One of the most intriguing storylines is Seattle’s passing game, particularly Jaxon Smith-Njigba’s performance. In their first meeting, the Cardinals were the only team to limit JSN to under 100 yards, holding him to a season-low 79. With Arizona’s secondary now stronger, Seattle may need to exploit the linebackers, as they did in the previous matchup when their tight ends combined for 53 yards and a touchdown. However, with AJ Barner and Eric Saubert sidelined, this strategy could be more challenging.

Another point of contention is the battle in the trenches. Arizona’s pass rush has been relentless, tallying 17 sacks this season, including five against the Cowboys. Walter Nolen, in particular, has been a force, recording 4 tackles, 2 TFLs, 1 sack, and more in his last game. Seattle’s offensive line, anchored by Anthony Bradford and Jalen Sundell, will face a stiff test. Conversely, the Seahawks’ ground game, which rushed for 155 yards in the first meeting, could be pivotal in controlling the tempo.

Defensively, Seattle’s pass rush will be critical, especially on third downs against Brissett, who tends to hold the ball longer than Murray. While less mobile, Brissett is harder to bring down, as evidenced by the Seahawks’ struggles against him in Week 2 of 2024. A bold question to consider: Can Seattle’s defense capitalize on Arizona’s recent struggles, particularly after allowing 5 sacks against the Cowboys?

One matchup to watch is Trey McBride against Nick Emmanwori. While Emmanwori has been solid in the nickel role, his ability to cover quicker slot receivers like McBride remains untested. This could be a breakout moment for either player.

In closing, this game is far from a guaranteed win for Seattle. History has shown that matchups between these two teams often produce unexpected results. While many fans may have penciled this in as a Seahawks victory, a loss here could significantly derail their playoff hopes. Will Seattle rise to the occasion, or will the Cardinals pull off an upset? The stage is set for a thrilling contest, and the outcome could shape the NFC West race. What do you think? Are the Seahawks overlooking the Cardinals, or will they secure the sweep? Let us know in the comments!

Seahawks vs. Cardinals Week 10 Preview: Can Seattle Sweep Arizona? (2026)
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